Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50343190'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50343190 (CHEMBL1773577 | N-(6-(2-(2-Fluorophenylsulfonamido...) Show SMILES CC(=O)Nc1nc2ccc(cc2s1)-c1ccnc(NS(=O)(=O)c2ccccc2F)n1 Show InChI InChI=1S/C19H14FN5O3S2/c1-11(26)22-19-24-15-7-6-12(10-16(15)29-19)14-8-9-21-18(23-14)25-30(27,28)17-5-3-2-4-13(17)20/h2-10H,1H3,(H,21,23,25)(H,22,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha expressed in Sf9 cells				J Med Chem 54: 1789-811 (2011) Article DOI: 10.1021/jm1014605 BindingDB Entry DOI: 10.7270/Q2TH8N1K
					More data for this Ligand-Target Pair