Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform' and Ligand = 'BDBM139732'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM139732 (US8895549, 34) Show SMILES COc1c(OC[C@H](O)CN2C[C@H](C)O[C@H](C)C2)ccc2C3=NCCN3C(NC(=O)c3cncs3)=Nc12 |r,c:36,t:21| Show InChI InChI=1S/C24H30N6O5S/c1-14-9-29(10-15(2)35-14)11-16(31)12-34-18-5-4-17-20(21(18)33-3)27-24(30-7-6-26-22(17)30)28-23(32)19-8-25-13-36-19/h4-5,8,13-16,31H,6-7,9-12H2,1-3H3,(H,27,28,32)/t14-,15+,16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.21	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was...				US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF
					More data for this Ligand-Target Pair