Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform' and Ligand = 'BDBM50393356'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50393356 (CHEMBL2152147) Show SMILES CNC(=O)c1nc(cnc1N)-c1cccc(c1)S(=O)(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C18H16ClN5O3S/c1-21-18(25)16-17(20)22-10-15(23-16)11-4-2-7-14(8-11)28(26,27)24-13-6-3-5-12(19)9-13/h2-10,24H,1H3,(H2,20,22)(H,21,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Exelixis Curated by ChEMBL					Assay Description Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...				J Med Chem 55: 5467-82 (2012) Article DOI: 10.1021/jm300403a BindingDB Entry DOI: 10.7270/Q2DF6S9N
					More data for this Ligand-Target Pair