Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM25083'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM25083 (6-(1H-indol-4-yl)-pteridin-2,4-diamine | 6-(1H-ind...) Show SMILES Nc1nc(N)c2nc(cnc2n1)-c1cccc2[nH]ccc12 Show InChI InChI=1S/C14H11N7/c15-12-11-13(21-14(16)20-12)18-6-10(19-11)7-2-1-3-9-8(7)4-5-17-9/h1-6,17H,(H4,15,16,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	7.4	22
TargeGen Inc.					Assay Description The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...				Proc Natl Acad Sci U S A 103: 19866-71 (2006) Article DOI: 10.1073/pnas.0606956103 BindingDB Entry DOI: 10.7270/Q2J101GM
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