Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM326283'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM326283 (US9637488, 66) Show SMILES Clc1cccc2cc(C3CCCN3c3ncnc4[nH]cnc34)c(nc12)N1CCOCC1 Show InChI InChI=1S/C22H22ClN7O/c23-16-4-1-3-14-11-15(21(28-18(14)16)29-7-9-31-10-8-29)17-5-2-6-30(17)22-19-20(25-12-24-19)26-13-27-22/h1,3-4,11-13,17H,2,5-10H2,(H,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...				US Patent US9637488 (2017) BindingDB Entry DOI: 10.7270/Q2D220Q6
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