Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM81369'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM81369 (SW13) Show SMILES Cc1ccccc1-n1c(Cn2nc(-c3cc(O)cc(F)c3)c3c(N)cccc23)nc2cccc(C)c2c1=O |(2.8,1.32,;2.8,2.86,;4.14,3.63,;4.14,5.17,;2.8,5.94,;1.47,5.17,;1.47,3.63,;.14,2.86,;.14,1.32,;1.47,.55,;1.47,-.99,;.27,-1.96,;.83,-3.4,;-.01,-4.69,;-1.5,-4.29,;-2.59,-5.38,;-4.13,-5.38,;-2.19,-6.87,;-.7,-7.26,;-.3,-8.75,;.39,-6.18,;2.36,-3.32,;3.45,-4.41,;3.05,-5.89,;4.94,-4.01,;5.34,-2.52,;4.25,-1.43,;2.76,-1.83,;-1.2,.55,;-2.53,1.32,;-3.86,.55,;-5.2,1.32,;-5.2,2.86,;-3.86,3.63,;-3.86,5.17,;-2.53,2.86,;-1.2,3.63,;-1.2,5.17,)| Show InChI InChI=1S/C30H24FN5O2/c1-17-7-3-4-11-24(17)36-26(33-23-10-5-8-18(2)27(23)30(36)38)16-35-25-12-6-9-22(32)28(25)29(34-35)19-13-20(31)15-21(37)14-19/h3-15,37H,16,32H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco					Assay Description Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series.				Chem Biol 17: 123-34 (2010) Article DOI: 10.1016/j.chembiol.2010.01.010 BindingDB Entry DOI: 10.7270/Q2CR5RVT
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