Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Phosphodiesterase' and Ligand = 'BDBM50204595'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Macaca mulatta (Rhesus macaque))	BDBM50204595 (CHEMBL3889667 | US10285989, Example 94) Show SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)NC1(CC1)c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N4O2/c1-25(2)15-22-12(8-13(26)23-15)14(27)24-16(5-6-16)9-3-4-10(11(18)7-9)17(19,20)21/h3-4,7-8H,5-6H2,1-2H3,(H,24,27)(H,22,23,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of rhesus monkey PDE2A3 expressed in AD293 cells using FAM-labeled cAMP as substrate after 60 mins in presence of cGMP by florescence pola...				ACS Med Chem Lett 8: 17-18 (2017) Article DOI: 10.1021/acsmedchemlett.6b00514 BindingDB Entry DOI: 10.7270/Q24M96HP
					More data for this Ligand-Target Pair
Phosphodiesterase (Macaca mulatta (Rhesus macaque))	BDBM50204595 (CHEMBL3889667 | US10285989, Example 94) Show SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)NC1(CC1)c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N4O2/c1-25(2)15-22-12(8-13(26)23-15)14(27)24-16(5-6-16)9-3-4-10(11(18)7-9)17(19,20)21/h3-4,7-8H,5-6H2,1-2H3,(H,24,27)(H,22,23,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...				Bioorg Med Chem Lett 17: 4284-9 (2007) BindingDB Entry DOI: 10.7270/Q24Q7X9Z
					More data for this Ligand-Target Pair
Phosphodiesterase (Macaca mulatta (Rhesus macaque))	BDBM50204595 (CHEMBL3889667 | US10285989, Example 94) Show SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)NC1(CC1)c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N4O2/c1-25(2)15-22-12(8-13(26)23-15)14(27)24-16(5-6-16)9-3-4-10(11(18)7-9)17(19,20)21/h3-4,7-8H,5-6H2,1-2H3,(H,24,27)(H,22,23,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...				Bioorg Med Chem Lett 17: 4284-9 (2007) BindingDB Entry DOI: 10.7270/Q24Q7X9Z
					More data for this Ligand-Target Pair