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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 5A' and Ligand = 'BDBM50134098'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 5A


(Bos taurus)
BDBM50134098
PNG
((3aR,10S)-2-Cyclohexyl-10-(4-methoxy-phenyl)-3a,4,...)
Show SMILES COc1ccc(cc1)[C@H]1c2[nH]c3ccccc3c2Cc2c(O)n(C3CCCCC3)c(=O)n12
Show InChI InChI=1S/C26H27N3O3/c1-32-18-13-11-16(12-14-18)24-23-20(19-9-5-6-10-21(19)27-23)15-22-25(30)28(26(31)29(22)24)17-7-3-2-4-8-17/h5-6,9-14,17,24,27,30H,2-4,7-8,15H2,1H3/t24-/m0/s1
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PC cid
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Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Inhibitory activity against bovine PDE5 (phosphodiesterase-5).


J Med Chem 46: 4525-32 (2003)


Article DOI: 10.1021/jm030056e
BindingDB Entry DOI: 10.7270/Q2NP255G
More data for this
Ligand-Target Pair