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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 5A' and Ligand = 'BDBM50134135'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 5A


(Bos taurus)
BDBM50134135
PNG
((5R,6R)-2-Cyclopropylmethyl-6-(4-methoxy-phenyl)-2...)
Show SMILES COc1ccc(cc1)[C@H]1N2[C@H](Cc3c1[nH]c1ccccc31)C(=O)N(CC1CC1)CC2=O
Show InChI InChI=1S/C25H25N3O3/c1-31-17-10-8-16(9-11-17)24-23-19(18-4-2-3-5-20(18)26-23)12-21-25(30)27(13-15-6-7-15)14-22(29)28(21)24/h2-5,8-11,15,21,24,26H,6-7,12-14H2,1H3/t21-,24-/m1/s1
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Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against bovine phosphodiesterase 5


J Med Chem 46: 4533-42 (2003)


Article DOI: 10.1021/jm0300577
BindingDB Entry DOI: 10.7270/Q2N015X2
More data for this
Ligand-Target Pair