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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM306536'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasma kallikrein


(Homo sapiens (Human))		BDBM306536
PNG
((1R,8S)-N-[(6-amino-2,4- dimethylpyridin-3-yl)meth...)
Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2[C@H]3O[C@H](c4cc(Cn5cc(Cl)cn5)ccc34)c2c1 |r|
Show InChI InChI=1S/C27H24ClN5O2/c1-14-7-24(29)32-15(2)23(14)11-30-27(34)17-4-6-20-22(9-17)26-21-8-16(3-5-19(21)25(20)35-26)12-33-13-18(28)10-31-33/h3-10,13,25-26H,11-12H2,1-2H3,(H2,29,32)(H,30,34)/t25-,26+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Global Blood Therapeutics, Inc.

US Patent


Assay Description
The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...

US Patent US10144746 (2018)


BindingDB Entry DOI: 10.7270/Q2J38VNH
More data for this
Ligand-Target Pair