BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM306654'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasma kallikrein


(Homo sapiens (Human))		BDBM306654
PNG
((1R,8S)-N-[(4-carbamimidoyl- 2,6-difluoro-phenyl)m...)
Show SMILES CC(C)c1ccc2[C@@H]3O[C@H](c2c1)c1cc(ccc31)C(=O)NCc1c(F)cc(cc1F)C(N)=N |r|
Show InChI InChI=1S/C26H23F2N3O2/c1-12(2)13-3-5-16-18(7-13)24-19-8-14(4-6-17(19)23(16)33-24)26(32)31-11-20-21(27)9-15(25(29)30)10-22(20)28/h3-10,12,23-24H,11H2,1-2H3,(H3,29,30)(H,31,32)/t23-,24+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Global Blood Therapeutics, Inc.

US Patent


Assay Description
The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...

US Patent US10144746 (2018)


BindingDB Entry DOI: 10.7270/Q2J38VNH
More data for this
Ligand-Target Pair