Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM306678'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM306678 ((+-)-N-[(6-amino-2,4-dimethyl- pyridin-3-yl)methyl...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccc2C3OC(c2c1)c1cc(c(C=C)cc31)-c1ccc(F)cc1F Show InChI InChI=1S/C31H25F2N3O2/c1-4-17-10-24-25(13-22(17)20-8-6-19(32)12-27(20)33)30-23-11-18(5-7-21(23)29(24)38-30)31(37)35-14-26-15(2)9-28(34)36-16(26)3/h4-13,29-30H,1,14H2,2-3H3,(H2,34,36)(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.69	n/a	n/a	n/a	n/a	n/a	n/a
Global Blood Therapeutics, Inc. US Patent					Assay Description The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...				US Patent US10144746 (2018) BindingDB Entry DOI: 10.7270/Q2J38VNH
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