Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Plasminogen' and Ligand = 'BDBM50032954'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50032954 (5-(piperidin-4-yl)isoxazol-3-ol | 5-Piperidin-4-yl...) Show SMILES O=c1cc(o[nH]1)C1CCNCC1 Show InChI InChI=1S/C8H12N2O2/c11-8-5-7(12-10-8)6-1-3-9-4-2-6/h5-6,9H,1-4H2,(H,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to full length Glu-plasminogen in human plasma assessed as inhibition of interaction with fibrin in presence of tPA				ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50032954 (5-(piperidin-4-yl)isoxazol-3-ol | 5-Piperidin-4-yl...) Show SMILES O=c1cc(o[nH]1)C1CCNCC1 Show InChI InChI=1S/C8H12N2O2/c11-8-5-7(12-10-8)6-1-3-9-4-2-6/h5-6,9H,1-4H2,(H,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of plasminogen/fibrinogen interaction in pooled citrated human platelet-poor plasma assessed as inhibition of lysis of CaCl2/t-PA-induced ...				J Med Chem 56: 3273-80 (2013) Article DOI: 10.1021/jm301818g BindingDB Entry DOI: 10.7270/Q2F47QGN
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50032954 (5-(piperidin-4-yl)isoxazol-3-ol | 5-Piperidin-4-yl...) Show SMILES O=c1cc(o[nH]1)C1CCNCC1 Show InChI InChI=1S/C8H12N2O2/c11-8-5-7(12-10-8)6-1-3-9-4-2-6/h5-6,9H,1-4H2,(H,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Glu-plasminogen/fibrinogen interaction in HEPES buffer assessed as inhibition of lysis of thrombin-induced clot preincubated for ...				J Med Chem 56: 3273-80 (2013) Article DOI: 10.1021/jm301818g BindingDB Entry DOI: 10.7270/Q2F47QGN
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50032954 (5-(piperidin-4-yl)isoxazol-3-ol | 5-Piperidin-4-yl...) Show SMILES O=c1cc(o[nH]1)C1CCNCC1 Show InChI InChI=1S/C8H12N2O2/c11-8-5-7(12-10-8)6-1-3-9-4-2-6/h5-6,9H,1-4H2,(H,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human full length Glu-plasminogen in buffer assessed as inhibition of interaction with fibrin preincubated for 15 mins followed b...				ACS Med Chem Lett 5: 538-43 (2014) Article DOI: 10.1021/ml400526d BindingDB Entry DOI: 10.7270/Q2QJ7JV4
					More data for this Ligand-Target Pair