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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasminogen' and Ligand = 'BDBM50292271'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasminogen


(Homo sapiens (Human))		BDBM50292271
PNG
(CHEMBL265127 | Cyclohexanone derivative)
Show SMILES COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC[C@H]1CCC[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OCc2ccccc2)C(=O)[C@@H](N)Cc2c[nH]c3ccccc23)C(=O)[C@@H](N)Cc2c[nH]c3ccccc23)C1=O)C(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)[C@@H](N)Cc1ccc(O)cc1
Show InChI InChI=1S/C68H74N12O14/c1-93-67(91)58(63(87)46(69)28-36-22-25-42(81)26-23-36)79-65(89)55(60(84)47(70)29-39-32-73-50-18-8-5-15-43(39)50)77-54(82)27-24-38-14-11-21-53(59(38)83)76-64(88)56(61(85)48(71)30-40-33-74-51-19-9-6-16-44(40)51)78-66(90)57(80-68(92)94-35-37-12-3-2-4-13-37)62(86)49(72)31-41-34-75-52-20-10-7-17-45(41)52/h2-10,12-13,15-20,22-23,25-26,32-34,38,46-49,53,55-58,73-75,81H,11,14,21,24,27-31,35,69-72H2,1H3,(H,76,88)(H,77,82)(H,78,90)(H,79,89)(H,80,92)/t38-,46+,47+,48+,49+,53-,55+,56+,57+,58+/m1/s1
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MMDB

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Similars
Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



Brown University

Curated by ChEMBL


Assay Description
Inhibitory concentration against plasmin

J Med Chem 48: 6908-17 (2005)


Article DOI: 10.1021/jm050488k
BindingDB Entry DOI: 10.7270/Q24M959K
More data for this
Ligand-Target Pair