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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50011613'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50011613
PNG
(1-{3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1c2ccccc2[nH]c1=O)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C25H17ClN6OS/c1-15-29-30-22-14-27-23(17-8-2-3-9-19(17)26)18-13-16(34-24(18)32(15)22)7-6-12-31-21-11-5-4-10-20(21)28-25(31)33/h2-5,8-11,13H,12,14H2,1H3,(H,28,33)
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Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay


J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair