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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50011655'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50011655
PNG
(6-Chloro-4-{3-[4-(2-chloro-phenyl)-9-methyl-6H-1-t...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CCN1C(=O)COc2ccc(Cl)cc12)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C26H17Cl2N5O2S/c1-15-30-31-23-13-29-25(18-6-2-3-7-20(18)28)19-12-17(36-26(19)33(15)23)5-4-10-32-21-11-16(27)8-9-22(21)35-14-24(32)34/h2-3,6-9,11-12H,10,13-14H2,1H3
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n/an/a 5n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay


J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair