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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50011877'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50011877
PNG
(4-(2-Chloro-phenyl)-9-methyl-2-trimethylsilanyleth...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#C[Si](C)(C)C)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C20H19ClN4SSi/c1-13-23-24-18-12-22-19(15-7-5-6-8-17(15)21)16-11-14(9-10-27(2,3)4)26-20(16)25(13)18/h5-8,11H,12H2,1-4H3
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n/an/a 20n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.


J Med Chem 34: 1440-6 (1991)


BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair