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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50038779'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50038779
PNG
(3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-ind...)
Show SMILES CC(C)(C)NC(=O)n1cc(C(=O)[C@@H]2CSC(N2)c2cccnc2)c2ccccc12
Show InChI InChI=1S/C22H24N4O2S/c1-22(2,3)25-21(28)26-12-16(15-8-4-5-9-18(15)26)19(27)17-13-29-20(24-17)14-7-6-10-23-11-14/h4-12,17,20,24H,13H2,1-3H3,(H,25,28)/t17-,20?/m0/s1
MMDB

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PC cid
PC sid
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PubMed
8.80n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand


J Med Chem 37: 2011-32 (1994)


BindingDB Entry DOI: 10.7270/Q2GH9JM7
More data for this
Ligand-Target Pair