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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50062045'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50062045
PNG
(6-Benzofuran-2-yl-1-dimethylcarbamoyl-3-[4-(2-meth...)
Show SMILES COC(=O)c1cc(cc2n(cc(C(=O)c3ccc(Cn4c(C)nc5cnccc45)cc3)c12)C(=O)N(C)C)-c1cc2ccccc2o1
Show InChI InChI=1S/C36H29N5O5/c1-21-38-28-18-37-14-13-29(28)40(21)19-22-9-11-23(12-10-22)34(42)27-20-41(36(44)39(2)3)30-16-25(15-26(33(27)30)35(43)45-4)32-17-24-7-5-6-8-31(24)46-32/h5-18,20H,19H2,1-4H3
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Article
PubMed
0.780n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranes


J Med Chem 41: 74-95 (1998)


Article DOI: 10.1021/jm970389+
BindingDB Entry DOI: 10.7270/Q2MC8Z4D
More data for this
Ligand-Target Pair