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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50284388'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284388
PNG
(2-{[Acetyl-(1-hexadecylcarbamoyloxymethyl-cyclopen...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CCCC1
Show InChI InChI=1S/C35H59N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-21-26-36-33(40)42-29-35(24-19-20-25-35)30-43-34(41)38(31(3)39)28-32-23-18-22-27-37(32)5-2/h18,22-23,27H,4-17,19-21,24-26,28-30H2,1-3H3/p+1
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PC cid
PC sid
UniChem
Article
1.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability to displace [3H]-PAF from its Platelet Activating Factor (PAF) receptor in rabbit platelet membrane in vitro.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Cavia porcellus)
BDBM50284388
PNG
(2-{[Acetyl-(1-hexadecylcarbamoyloxymethyl-cyclopen...)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CCCC1
Show InChI InChI=1S/C35H59N3O5/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-21-26-36-33(40)42-29-35(24-19-20-25-35)30-43-34(41)38(31(3)39)28-32-23-18-22-27-37(32)5-2/h18,22-23,27H,4-17,19-21,24-26,28-30H2,1-3H3/p+1
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UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 350n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against PAF-induced aggregation of rabbit platelets.


Bioorg Med Chem Lett 5: 1091-1096 (1995)


Article DOI: 10.1016/0960-894X(95)00173-Q
BindingDB Entry DOI: 10.7270/Q2SQ90BW
More data for this
Ligand-Target Pair