Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM21103'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM21103 (3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...) Show SMILES COc1ccc(-c2ccc(NC(=O)Nc3cc(C)ccc3F)cc2)c2c(N)noc12 Show InChI InChI=1S/C22H19FN4O3/c1-12-3-9-16(23)17(11-12)26-22(28)25-14-6-4-13(5-7-14)15-8-10-18(29-2)20-19(15)21(24)27-30-20/h3-11H,1-2H3,(H2,24,27)(H2,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair