Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM227951'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM227951 (8-{[(3R)-3-Aminopiperidin-1-yl]methyl}-4-[(2-fluor...) Show SMILES Cc1cc(F)c(Nc2ccnc3Nc4ccc(CN5CCC[C@@H](N)C5)cc4NC(=O)c23)cc1O |r| Show InChI InChI=1S/C25H27FN6O2/c1-14-9-17(26)20(11-22(14)33)29-19-6-7-28-24-23(19)25(34)31-21-10-15(4-5-18(21)30-24)12-32-8-2-3-16(27)13-32/h4-7,9-11,16,33H,2-3,8,12-13,27H2,1H3,(H,31,34)(H2,28,29,30)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.829	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human PDGFRβ (amino acids R561-L1106), expr...				US Patent US10047096 (2018) BindingDB Entry DOI: 10.7270/Q23R0VW4
					More data for this Ligand-Target Pair