Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4056'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4056 (2-[2-amino-6-(2,6-dichlorophenyl)-7-oxo-7H,8H-pyri...) Show SMILES Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(CC(O)=O)c2n1 |(-6.98,-1.25,;-5.65,-.48,;-5.65,1.06,;-4.32,1.83,;-2.98,1.06,;-1.65,1.83,;-.32,1.06,;1.02,1.83,;1.02,3.37,;-.32,4.14,;2.35,4.14,;3.69,3.37,;3.69,1.83,;2.35,1.06,;2.35,-.48,;-.32,-.48,;1.02,-1.25,;-1.65,-1.25,;-1.65,-2.79,;-.32,-3.56,;1.02,-2.79,;-.32,-5.1,;-2.98,-.48,;-4.32,-1.25,)| Show InChI InChI=1S/C15H10Cl2N4O3/c16-9-2-1-3-10(17)12(9)8-4-7-5-19-15(18)20-13(7)21(14(8)24)6-11(22)23/h1-5H,6H2,(H,22,23)(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	25
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 41: 4365-77 (1998) Article DOI: 10.1021/jm980398y BindingDB Entry DOI: 10.7270/Q2CC0XWN
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