Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4059'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4059 (2-Amino-6-(2,6-dichlorophenyl)-8-(3-dimethylaminop...) Show SMILES CN(C)CCCn1c2nc(N)ncc2cc(-c2c(Cl)cccc2Cl)c1=O |(1.02,-7.41,;1.02,-5.87,;2.35,-5.1,;-.32,-5.1,;-.32,-3.56,;-1.65,-2.79,;-1.65,-1.25,;-2.98,-.48,;-4.32,-1.25,;-5.65,-.48,;-6.98,-1.25,;-5.65,1.06,;-4.32,1.83,;-2.98,1.06,;-1.65,1.83,;-.32,1.06,;1.02,1.83,;1.02,3.37,;-.32,4.14,;2.35,4.14,;3.69,3.37,;3.69,1.83,;2.35,1.06,;2.35,-.48,;-.32,-.48,;1.02,-1.25,)| Show InChI InChI=1S/C18H19Cl2N5O/c1-24(2)7-4-8-25-16-11(10-22-18(21)23-16)9-12(17(25)26)15-13(19)5-3-6-14(15)20/h3,5-6,9-10H,4,7-8H2,1-2H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 41: 4365-77 (1998) Article DOI: 10.1021/jm980398y BindingDB Entry DOI: 10.7270/Q2CC0XWN
					More data for this Ligand-Target Pair