Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM47167 (CHEMBL201511 | US8957103, Z1 | US9364459, A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard Karls University Curated by ChEMBL | Assay Description Inhibition of human PDGFR beta | J Med Chem 49: 7549-53 (2006) Article DOI: 10.1021/jm0609871 BindingDB Entry DOI: 10.7270/Q2NZ8794 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM47167 (CHEMBL201511 | US8957103, Z1 | US9364459, A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard-Karls University Curated by ChEMBL | Assay Description Inhibition of human recombinant PDGFRbeta | J Med Chem 51: 3814-24 (2008) Article DOI: 10.1021/jm8001185 BindingDB Entry DOI: 10.7270/Q2057FQS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM47167 (CHEMBL201511 | US8957103, Z1 | US9364459, A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hadassah Hebrew University Hospital Curated by ChEMBL | Assay Description Inhibition of PDGFRbeta after 80 mins by radiometric protein kinase assay | Bioorg Med Chem 18: 612-20 (2010) Article DOI: 10.1016/j.bmc.2009.12.004 BindingDB Entry DOI: 10.7270/Q2DB820N | |||||||||||
More data for this Ligand-Target Pair |