Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4874'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4874 (1-(3-Methoxyanilino)-4-(4-pyridylmethyl)phthalazin...) Show SMILES COc1cccc(Nc2nnc(Cc3ccncc3)c3ccccc23)c1 Show InChI InChI=1S/C21H18N4O/c1-26-17-6-4-5-16(14-17)23-21-19-8-3-2-7-18(19)20(24-25-21)13-15-9-11-22-12-10-15/h2-12,14H,13H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description The autophosphorylation assay was performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified ov...				J Med Chem 43: 2310-23 (2000) Article DOI: 10.1021/jm9909443 BindingDB Entry DOI: 10.7270/Q24M92R5
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