Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4886'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4886 (3-(2-{[(3Z)-6-(3-ethoxyphenyl)-2-oxo-2,3-dihydro-1...) Show SMILES CCOc1cccc(c1)-c1ccc2\C(=C\c3[nH]cc(C)c3CCC(O)=O)C(=O)Nc2c1 Show InChI InChI=1S/C25H24N2O4/c1-3-31-18-6-4-5-16(11-18)17-7-8-20-21(25(30)27-23(20)12-17)13-22-19(9-10-24(28)29)15(2)14-26-22/h4-8,11-14,26H,3,9-10H2,1-2H3,(H,27,30)(H,28,29)/b21-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc.					Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...				J Med Chem 42: 5120-30 (1999) Article DOI: 10.1021/jm9904295 BindingDB Entry DOI: 10.7270/Q20Z71GM
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