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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4889'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM4889
PNG
(3-(4-methyl-5-{[(3Z)-2-oxo-5-sulfamoyl-2,3-dihydro...)
Show SMILES Cc1c(CCC(O)=O)c[nH]c1\C=C1/C(=O)Nc2ccc(cc12)S(N)(=O)=O
Show InChI InChI=1S/C17H17N3O5S/c1-9-10(2-5-16(21)22)8-19-15(9)7-13-12-6-11(26(18,24)25)3-4-14(12)20-17(13)23/h3-4,6-8,19H,2,5H2,1H3,(H,20,23)(H,21,22)(H2,18,24,25)/b13-7-
PDB
MMDB

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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 5.98E+3n/an/an/an/an/an/a



SUGEN, Inc.



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...


J Med Chem 42: 5120-30 (1999)


Article DOI: 10.1006/jmbi.2001.4516
BindingDB Entry DOI: 10.7270/Q20Z71GM
More data for this
Ligand-Target Pair