Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM4891 (3-(4-methyl-5-{[(3Z)-2-oxo-6-phenyl-2,3-dihydro-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | J Med Chem 42: 5120-30 (1999) Article DOI: 10.1021/jm9904295 BindingDB Entry DOI: 10.7270/Q20Z71GM | |||||||||||
More data for this Ligand-Target Pair |