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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4894'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM4894
PNG
(3-(5-{[(3Z)-6-(4-methoxyphenyl)-2-oxo-2,3-dihydro-...)
Show SMILES COc1ccc(cc1)-c1ccc2\C(=C\c3[nH]cc(CCC(O)=O)c3C)C(=O)Nc2c1
Show InChI InChI=1S/C24H22N2O4/c1-14-17(6-10-23(27)28)13-25-21(14)12-20-19-9-5-16(11-22(19)26-24(20)29)15-3-7-18(30-2)8-4-15/h3-5,7-9,11-13,25H,6,10H2,1-2H3,(H,26,29)(H,27,28)/b20-12-
PDB
MMDB

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Article
PubMed
n/an/a 3.08E+3n/an/an/an/an/an/a



SUGEN, Inc.



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...


J Med Chem 42: 5120-30 (1999)


Article DOI: 10.1006/jmbi.2001.4516
BindingDB Entry DOI: 10.7270/Q20Z71GM
More data for this
Ligand-Target Pair