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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50069102'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50069102
PNG
(CHEMBL3403510 | US10189853, Compound 3)
Show SMILES COc1ccc(cc1OC)N(C)c1nc(C)nc2oc(C)cc12
Show InChI InChI=1S/C17H19N3O3/c1-10-8-13-16(18-11(2)19-17(13)23-10)20(3)12-6-7-14(21-4)15(9-12)22-5/h6-9H,1-5H3
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Article
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n/an/a 66n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of PDGFR-beta in human U251 cells compound pretreated for 60 min before PDGF-BB stimulation for 10 mins by phosphotyrosine ELISA cytoblot ...

Bioorg Med Chem 23: 2408-23 (2015)


Article DOI: 10.1016/j.bmc.2015.03.061
BindingDB Entry DOI: 10.7270/Q2765H1D
More data for this
Ligand-Target Pair