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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50115316'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50115316
PNG
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Show SMILES CCc1ccc(NC(=O)N2CCN(CC2)c2ncnc3cc(OC)c(OC)cc23)cc1
Show InChI InChI=1S/C23H27N5O3/c1-4-16-5-7-17(8-6-16)26-23(29)28-11-9-27(10-12-28)22-18-13-20(30-2)21(31-3)14-19(18)24-15-25-22/h5-8,13-15H,4,9-12H2,1-3H3,(H,26,29)
PDB
MMDB

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PC cid
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PubMed
n/an/a 1.21E+3n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor beta phosphorylation


J Med Chem 45: 3057-66 (2002)


BindingDB Entry DOI: 10.7270/Q2RX9BDP
More data for this
Ligand-Target Pair