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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50115344'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50115344
PNG
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Show SMILES CCCCc1ccc(NC(=O)N2CCN(CC2)c2ncnc3cc(OC)c(OC)cc23)cc1
Show InChI InChI=1S/C25H31N5O3/c1-4-5-6-18-7-9-19(10-8-18)28-25(31)30-13-11-29(12-14-30)24-20-15-22(32-2)23(33-3)16-21(20)26-17-27-24/h7-10,15-17H,4-6,11-14H2,1-3H3,(H,28,31)
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n/an/a 210n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor beta phosphorylation


J Med Chem 45: 3057-66 (2002)


BindingDB Entry DOI: 10.7270/Q2RX9BDP
More data for this
Ligand-Target Pair