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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50115349'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50115349
PNG
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Show SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc(cc4)[N+]([O-])=O)cc3)c2cc1OC
Show InChI InChI=1S/C27H26N6O6/c1-37-24-15-22-23(16-25(24)38-2)28-17-29-26(22)31-11-13-32(14-12-31)27(34)30-18-3-7-20(8-4-18)39-21-9-5-19(6-10-21)33(35)36/h3-10,15-17H,11-14H2,1-2H3,(H,30,34)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor beta phosphorylation


J Med Chem 45: 3057-66 (2002)


BindingDB Entry DOI: 10.7270/Q2RX9BDP
More data for this
Ligand-Target Pair