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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50117322'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50117322
PNG
(4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...)
Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc(C)cc4)cc3)c2cc1OCCOC
Show InChI InChI=1S/C32H37N5O6/c1-23-4-8-25(9-5-23)43-26-10-6-24(7-11-26)35-32(38)37-14-12-36(13-15-37)31-27-20-29(41-18-16-39-2)30(42-19-17-40-3)21-28(27)33-22-34-31/h4-11,20-22H,12-19H2,1-3H3,(H,35,38)
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MMDB

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PC cid
PC sid
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PubMed
n/an/a 26n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma


J Med Chem 45: 3772-93 (2002)


BindingDB Entry DOI: 10.7270/Q2WW7JD9
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50117322
PNG
(4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...)
Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc(C)cc4)cc3)c2cc1OCCOC
Show InChI InChI=1S/C32H37N5O6/c1-23-4-8-25(9-5-23)43-26-10-6-24(7-11-26)35-32(38)37-14-12-36(13-15-37)31-27-20-29(41-18-16-39-2)30(42-19-17-40-3)21-28(27)33-22-34-31/h4-11,20-22H,12-19H2,1-3H3,(H,35,38)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 206n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma


J Med Chem 45: 3772-93 (2002)


BindingDB Entry DOI: 10.7270/Q2WW7JD9
More data for this
Ligand-Target Pair