Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50117352'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117352 (4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C29H31N5O5/c1-36-16-17-38-27-19-25-24(18-26(27)37-2)28(31-20-30-25)33-12-14-34(15-13-33)29(35)32-21-8-10-23(11-9-21)39-22-6-4-3-5-7-22/h3-11,18-20H,12-17H2,1-2H3,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...				J Med Chem 46: 4910-25 (2003) Article DOI: 10.1021/jm020505v BindingDB Entry DOI: 10.7270/Q2X929PJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117352 (4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C29H31N5O5/c1-36-16-17-38-27-19-25-24(18-26(27)37-2)28(31-20-30-25)33-12-14-34(15-13-33)29(35)32-21-8-10-23(11-9-21)39-22-6-4-3-5-7-22/h3-11,18-20H,12-17H2,1-2H3,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117352 (4-[6-Methoxy-7-(2-methoxy-ethoxy)-quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C29H31N5O5/c1-36-16-17-38-27-19-25-24(18-26(27)37-2)28(31-20-30-25)33-12-14-34(15-13-33)29(35)32-21-8-10-23(11-9-21)39-22-6-4-3-5-7-22/h3-11,18-20H,12-17H2,1-2H3,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	525	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair