Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50117377'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117377 (4-{7-[3-(4,4-Difluoro-piperidin-1-yl)-propoxy]-6-m...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCC(F)(F)CC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C31H40F2N6O4/c1-22(2)43-24-7-5-23(6-8-24)36-30(40)39-16-14-38(15-17-39)29-25-19-27(41-3)28(20-26(25)34-21-35-29)42-18-4-11-37-12-9-31(32,33)10-13-37/h5-8,19-22H,4,9-18H2,1-3H3,(H,36,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50117377 (4-{7-[3-(4,4-Difluoro-piperidin-1-yl)-propoxy]-6-m...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCC(F)(F)CC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1 Show InChI InChI=1S/C31H40F2N6O4/c1-22(2)43-24-7-5-23(6-8-24)36-30(40)39-16-14-38(15-17-39)29-25-19-27(41-3)28(20-26(25)34-21-35-29)42-18-4-11-37-12-9-31(32,33)10-13-37/h5-8,19-22H,4,9-18H2,1-3H3,(H,36,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 45: 3772-93 (2002) BindingDB Entry DOI: 10.7270/Q2WW7JD9
					More data for this Ligand-Target Pair