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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50134894'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134894
PNG
(4-(8-Oxo-8,9-dihydro-7H-purin-6-yl)-piperazine-1-c...)
Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(CC1)c1ncnc2[nH]c(=O)[nH]c12
Show InChI InChI=1S/C22H21N7O3/c30-21-26-18-19(27-21)23-14-24-20(18)28-10-12-29(13-11-28)22(31)25-15-6-8-17(9-7-15)32-16-4-2-1-3-5-16/h1-9,14H,10-13H2,(H,25,31)(H2,23,24,26,27,30)
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair