Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50152355'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152355 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)NCc3ccc(nc3)C(F)(F)F)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C31H36F3N7O2S/c1-42-26-16-24-25(17-27(26)43-15-5-10-39-8-3-2-4-9-39)36-21-23(18-35)29(24)40-11-13-41(14-12-40)30(44)38-20-22-6-7-28(37-19-22)31(32,33)34/h6-7,16-17,19,21H,2-5,8-15,20H2,1H3,(H,38,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152355 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)NCc3ccc(nc3)C(F)(F)F)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C31H36F3N7O2S/c1-42-26-16-24-25(17-27(26)43-15-5-10-39-8-3-2-4-9-39)36-21-23(18-35)29(24)40-11-13-41(14-12-40)30(44)38-20-22-6-7-28(37-19-22)31(32,33)34/h6-7,16-17,19,21H,2-5,8-15,20H2,1H3,(H,38,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152355 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)NCc3ccc(nc3)C(F)(F)F)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C31H36F3N7O2S/c1-42-26-16-24-25(17-27(26)43-15-5-10-39-8-3-2-4-9-39)36-21-23(18-35)29(24)40-11-13-41(14-12-40)30(44)38-20-22-6-7-28(37-19-22)31(32,33)34/h6-7,16-17,19,21H,2-5,8-15,20H2,1H3,(H,38,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Platelet derived growth factor receptor beta autophosphorylation in CHO cells				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair