Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50152380'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152380 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)Nc1ccncc1 Show InChI InChI=1S/C26H33N7O2S/c1-34-23-17-21-22(18-24(23)35-16-15-31-9-3-2-4-10-31)28-19-29-25(21)32-11-13-33(14-12-32)26(36)30-20-5-7-27-8-6-20/h5-8,17-19H,2-4,9-16H2,1H3,(H,27,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152380 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)Nc1ccncc1 Show InChI InChI=1S/C26H33N7O2S/c1-34-23-17-21-22(18-24(23)35-16-15-31-9-3-2-4-10-31)28-19-29-25(21)32-11-13-33(14-12-32)26(36)30-20-5-7-27-8-6-20/h5-8,17-19H,2-4,9-16H2,1H3,(H,27,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152380 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)Nc1ccncc1 Show InChI InChI=1S/C26H33N7O2S/c1-34-23-17-21-22(18-24(23)35-16-15-31-9-3-2-4-10-31)28-19-29-25(21)32-11-13-33(14-12-32)26(36)30-20-5-7-27-8-6-20/h5-8,17-19H,2-4,9-16H2,1H3,(H,27,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Platelet derived growth factor receptor beta autophosphorylation in CHO cells				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair