Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50181320 (4-Amino-3-[6-(4-methylpiperazinyl)benzimidazol-2-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of human recombinant PDGFRbeta | J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Mus musculus (mouse)) | BDBM50181320 (4-Amino-3-[6-(4-methylpiperazinyl)benzimidazol-2-y...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation Curated by ChEMBL | Assay Description Inhibitory activity against PDGFRbeta | Bioorg Med Chem Lett 16: 2247-51 (2006) Article DOI: 10.1016/j.bmcl.2006.01.020 BindingDB Entry DOI: 10.7270/Q2NZ8777 | |||||||||||
More data for this Ligand-Target Pair |