Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50279080 ((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr)4:1 as substrate by ELISA | Eur J Med Chem 65: 477-86 (2013) Article DOI: 10.1016/j.ejmech.2013.05.002 BindingDB Entry DOI: 10.7270/Q2B27WQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50279080 ((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Austria GmbH Curated by ChEMBL | Assay Description Inhibition of human PDGFRbeta | Cancer Res 68: 4774-82 (2008) Article DOI: 10.1158/0008-5472.CAN-07-6307 BindingDB Entry DOI: 10.7270/Q26M3715 | |||||||||||
More data for this Ligand-Target Pair |