BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM6152'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Mus musculus (mouse))
BDBM6152
PNG
(1,6-naphthyridine 21 | 7-N-[4-(diethylamino)butyl]...)
Show SMILES CCN(CC)CCCCNc1cc2nc(N)c(cc2cn1)-c1cc(OC)cc(OC)c1
Show InChI InChI=1S/C24H33N5O2/c1-5-29(6-2)10-8-7-9-26-23-15-22-18(16-27-23)13-21(24(25)28-22)17-11-19(30-3)14-20(12-17)31-4/h11-16H,5-10H2,1-4H3,(H2,25,28)(H,26,27)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...


J Med Chem 48: 4628-53 (2005)


Article DOI: 10.1021/jm0500931
BindingDB Entry DOI: 10.7270/Q2DV1H3W
More data for this
Ligand-Target Pair