Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM6165'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM6165 (1,6-naphthyridine 34 | 3-tert-butyl-1-[3-(2,6-dich...) Show SMILES CN1CCN(CCCNc2cc3nc(NC(=O)NC(C)(C)C)c(cc3cn2)-c2c(Cl)cccc2Cl)CC1 |(-11.94,-2.96,;-10.6,-2.19,;-10.6,-.65,;-9.27,.12,;-7.94,-.65,;-6.85,.44,;-5.36,.04,;-4.27,1.13,;-2.78,.73,;-1.45,1.5,;-.12,.73,;1.22,1.5,;2.55,.73,;3.88,1.5,;5.22,.73,;5.22,-.81,;6.55,-1.58,;3.88,-1.58,;3.88,-3.12,;2.55,-3.89,;5.22,-3.89,;3.88,-4.66,;3.88,3.05,;2.55,3.82,;1.22,3.05,;-.12,3.82,;-1.45,3.05,;5.22,3.82,;6.52,3,;6.47,1.46,;7.88,3.72,;7.94,5.26,;6.63,6.08,;5.27,5.35,;3.97,6.17,;-7.94,-2.19,;-9.27,-2.96,)| Show InChI InChI=1S/C27H35Cl2N7O/c1-27(2,3)34-26(37)33-25-19(24-20(28)7-5-8-21(24)29)15-18-17-31-23(16-22(18)32-25)30-9-6-10-36-13-11-35(4)12-14-36/h5,7-8,15-17H,6,9-14H2,1-4H3,(H,30,31)(H2,32,33,34,37)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...				J Med Chem 48: 4628-53 (2005) Article DOI: 10.1021/jm0500931 BindingDB Entry DOI: 10.7270/Q2DV1H3W
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