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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM6176'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Mus musculus (mouse))		BDBM6176
PNG
(1,6-naphthyridine 42 | 1-(7-{[4-(benzyloxy)butyl]a...)
Show SMILES COc1cc(OC)cc(c1)-c1cc2cnc(NCCCCOCc3ccccc3)cc2nc1NC(=O)NC(C)(C)C
Show InChI InChI=1S/C32H39N5O4/c1-32(2,3)37-31(38)36-30-27(23-15-25(39-4)18-26(16-23)40-5)17-24-20-34-29(19-28(24)35-30)33-13-9-10-14-41-21-22-11-7-6-8-12-22/h6-8,11-12,15-20H,9-10,13-14,21H2,1-5H3,(H,33,34)(H2,35,36,37,38)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...

J Med Chem 48: 4628-53 (2005)


Article DOI: 10.1021/jm0500931
BindingDB Entry DOI: 10.7270/Q2DV1H3W
More data for this
Ligand-Target Pair