Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM6179'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM6179 (1,6-naphthyridine 76 | 3-tert-butyl-1-[3-(3,5-dime...) Show SMILES COc1cc(OC)cc(c1)-c1cc2cnc(NCCCCO)cc2nc1NC(=O)NC(C)(C)C Show InChI InChI=1S/C25H33N5O4/c1-25(2,3)30-24(32)29-23-20(16-10-18(33-4)13-19(11-16)34-5)12-17-15-27-22(14-21(17)28-23)26-8-6-7-9-31/h10-15,31H,6-9H2,1-5H3,(H,26,27)(H2,28,29,30,32)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...				J Med Chem 48: 4628-53 (2005) Article DOI: 10.1021/jm0500931 BindingDB Entry DOI: 10.7270/Q2DV1H3W
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