Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM6183'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM6183 (3,4-Dihydro-1,6-naphthyridine analogue 50 | N-[5-(...) Show SMILES COc1cc(OC)cc(c1)C1Cc2cnc(cc2N=C1NC(=O)NC(C)(C)C)N(CCCCCOCc1ccccc1)C(C)=O |c:20| Show InChI InChI=1S/C35H45N5O5/c1-24(41)40(15-11-8-12-16-45-23-25-13-9-7-10-14-25)32-21-31-27(22-36-32)19-30(26-17-28(43-5)20-29(18-26)44-6)33(37-31)38-34(42)39-35(2,3)4/h7,9-10,13-14,17-18,20-22,30H,8,11-12,15-16,19,23H2,1-6H3,(H2,37,38,39,42)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...				J Med Chem 48: 4628-53 (2005) Article DOI: 10.1021/jm0500931 BindingDB Entry DOI: 10.7270/Q2DV1H3W
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