Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM6185'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM6185 (3,4-Dihydro-1,6-naphthyridine analogue 52 | N-[2-[...) Show SMILES COc1cc(OC)cc(c1)C1Cc2cnc(cc2N=C1NC(=O)NC(C)(C)C)N(CCCCO)C(C)=O |c:20| Show InChI InChI=1S/C27H37N5O5/c1-17(34)32(9-7-8-10-33)24-15-23-19(16-28-24)13-22(18-11-20(36-5)14-21(12-18)37-6)25(29-23)30-26(35)31-27(2,3)4/h11-12,14-16,22,33H,7-10,13H2,1-6H3,(H2,29,30,31,35)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...				J Med Chem 48: 4628-53 (2005) Article DOI: 10.1021/jm0500931 BindingDB Entry DOI: 10.7270/Q2DV1H3W
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