Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM209853'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM209853 (US9273052, 1 | US9566277, 1) Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCn2c(C1)nnc2C(F)(F)F Show InChI InChI=1S/C22H16F4N6O2/c23-16-6-5-12(10-17-13-3-1-2-4-14(13)19(33)29-27-17)9-15(16)20(34)31-7-8-32-18(11-31)28-30-21(32)22(24,25)26/h1-6,9H,7-8,10-11H2,(H,29,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	25
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t...				US Patent US9566277 (2017) BindingDB Entry DOI: 10.7270/Q2Q24279
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM209853 (US9273052, 1 | US9566277, 1) Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCn2c(C1)nnc2C(F)(F)F Show InChI InChI=1S/C22H16F4N6O2/c23-16-6-5-12(10-17-13-3-1-2-4-14(13)19(33)29-27-17)9-15(16)20(34)31-7-8-32-18(11-31)28-30-21(32)22(24,25)26/h1-6,9H,7-8,10-11H2,(H,29,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	25
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...				US Patent US9273052 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MWG
					More data for this Ligand-Target Pair