Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27704'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27704 (3,5-diphenyl-4,5,7-triazatricyclo[7.4.0.0^{2,6}]tr...) Show SMILES O=c1[nH]c2n(nc(-c3ccccc3)c2c2CCCCc12)-c1ccccc1 Show InChI InChI=1S/C22H19N3O/c26-22-18-14-8-7-13-17(18)19-20(15-9-3-1-4-10-15)24-25(21(19)23-22)16-11-5-2-6-12-16/h1-6,9-12H,7-8,13-14H2,(H,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	23
Deltagen Research Laboratories					Assay Description To assess the inhibitory activity of novel inhibitors, the PARP-1 enzyme assay was carried out in reaction mixture consisting of Escherichia coli str...				Bioorg Med Chem Lett 18: 5126-9 (2008) Article DOI: 10.1016/j.bmcl.2008.07.091 BindingDB Entry DOI: 10.7270/Q29S1PCX
					More data for this Ligand-Target Pair